AIP-mutated acromegaly resistant to first-generation somatostatin analogs: long-term control with pasireotide LAR in two patients

Acromegaly is a rare disease due to chronic excess growth hormone (GH) and IGF-1. Aryl hydrocarbon receptor interacting protein (AIP) mutations are associated with an aggressive, inheritable form of acromegaly that responds poorly to SST2-specific somatostatin analogs (SSA). The role of pasireotide,...

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Detalles Bibliográficos
Autores principales: Daly, Adrian F, Rostomyan, Liliya, Betea, Daniela, Bonneville, Jean-François, Villa, Chiara, Pellegata, Natalia S, Waser, Beatrice, Reubi, Jean-Claude, Waeber Stephan, Catherine, Christ, Emanuel, Beckers, Albert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bioscientifica Ltd 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6454377/
https://www.ncbi.nlm.nih.gov/pubmed/30851160
http://dx.doi.org/10.1530/EC-19-0004

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