A pharmacogenetic study of patients with schizophrenia from West Siberia gets insight into dopaminergic mechanisms of antipsychotic-induced hyperprolactinemia

BACKGROUND: Hyperprolactinemia (HPRL) is a classical side effect of antipsychotic drugs primarily attributed to blockade of dopamine D2 receptors (DRD2s) on the membranes of lactotroph cells within the pituitary gland. Certain antipsychotic drugs, e.g. risperidone, are more likely to induce HPRL bec...

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Detalles Bibliográficos
Autores principales: Osmanova, Diana Z., Freidin, Maxim B., Fedorenko, Olga Yu., Pozhidaev, Ivan V., Boiko, Anastasiia S., Vyalova, Natalia M., Tiguntsev, Vladimir V., Kornetova, Elena G., Loonen, Anton J. M., Semke, Arkadiy V., Wilffert, Bob, Bokhan, Nikolay A., Ivanova, Svetlana A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6454588/
https://www.ncbi.nlm.nih.gov/pubmed/30967134
http://dx.doi.org/10.1186/s12881-019-0773-3

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