The CIMP-high phenotype is associated with energy metabolism alterations in colon adenocarcinoma

BACKGROUND: CpG island methylator phenotype (CIMP) is found in 15–20% of malignant colorectal tumors and is characterized by strong CpG hypermethylation over the genome. The molecular mechanisms of this phenomenon are not still fully understood. The development of CIMP is followed by global gene exp...

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Detalles Bibliográficos
Autores principales: Fedorova, Maria S., Krasnov, George S., Lukyanova, Elena N., Zaretsky, Andrew R., Dmitriev, Alexey A., Melnikova, Nataliya V., Moskalev, Alexey A., Kharitonov, Sergey L., Pudova, Elena A., Guvatova, Zulfiya G., Kobelyatskaya, Anastasiya A., Ishina, Irina A., Slavnova, Elena N., Lipatova, Anastasia V., Chernichenko, Maria A., Sidorov, Dmitry V., Popov, Anatoly Y., Kiseleva, Marina V., Kaprin, Andrey D., Snezhkina, Anastasiya V., Kudryavtseva, Anna V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6454590/
https://www.ncbi.nlm.nih.gov/pubmed/30967137
http://dx.doi.org/10.1186/s12881-019-0771-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6454590/
https://www.ncbi.nlm.nih.gov/pubmed/30967137
http://dx.doi.org/10.1186/s12881-019-0771-5

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