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The characterization of AD/PART co-pathology in CJD suggests independent pathogenic mechanisms and no cross-seeding between misfolded Aβ and prion proteins

Current evidence indicating a role of the human prion protein (PrP) in amyloid-beta (Aβ) formation or a synergistic effect between Aβ and prion pathology remains controversial. Conflicting results also concern the frequency of the association between the two protein misfolding disorders and the issu...

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Detalles Bibliográficos
Autores principales:	Rossi, Marcello, Kai, Hideaki, Baiardi, Simone, Bartoletti-Stella, Anna, Carlà, Benedetta, Zenesini, Corrado, Capellari, Sabina, Kitamoto, Tetsuyuki, Parchi, Piero
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6454607/ https://www.ncbi.nlm.nih.gov/pubmed/30961668 http://dx.doi.org/10.1186/s40478-019-0706-6

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