Next-generation sequencing for hypothesis-free genomic detection of invasive tropical infections in poly-microbially contaminated, formalin-fixed, paraffin-embedded tissue samples – a proof-of-principle assessment

BACKGROUND: The potential of next-generation sequencing (NGS) for hypothesis-free pathogen diagnosis from (poly-)microbially contaminated, formalin-fixed, paraffin embedded tissue samples from patients with invasive fungal infections and amebiasis was investigated. Samples from patients with chromob...

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Detalles Bibliográficos
Autores principales: Frickmann, Hagen, Künne, Carsten, Hagen, Ralf Matthias, Podbielski, Andreas, Normann, Jana, Poppert, Sven, Looso, Mario, Kreikemeyer, Bernd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6454699/
https://www.ncbi.nlm.nih.gov/pubmed/30961537
http://dx.doi.org/10.1186/s12866-019-1448-0

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