Neutrophil extracellular traps (NETs) exacerbate severity of infant sepsis

BACKGROUND: Neutrophil extracellular traps (NETs) are innate defense mechanisms that are also implicated in the pathogenesis of organ dysfunction. However, the role of NETs in pediatric sepsis is unknown. METHODS: Infant (2 weeks old) and adult (6 weeks old) mice were submitted to sepsis by intraper...

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Detalles Bibliográficos
Autores principales: Colón, David F., Wanderley, Carlos W., Franchin, Marcelo, Silva, Camila M., Hiroki, Carlos H., Castanheira, Fernanda V. S., Donate, Paula B., Lopes, Alexandre H., Volpon, Leila C., Kavaguti, Silvia K., Borges, Vanessa F., Speck-Hernandez, Cesar A., Ramalho, Fernando, Carlotti, Ana P., Carmona, Fabio, Alves-Filho, Jose C., Liew, Foo Y., Cunha, Fernando Q.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6454713/
https://www.ncbi.nlm.nih.gov/pubmed/30961634
http://dx.doi.org/10.1186/s13054-019-2407-8

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