Cargando…
Radiosensitization of orthotopic GIC-driven glioblastoma by doxycycline causes skin damage
Doxycycline (DXC) is a tetracycline antibiotic which has been proposed as a breast cancer radiosensitizer by specifically reducing the expression of the DNA repair enzyme DNA PK in breast cancer initiating cells. Since DXC presents favorable pharmacokinetics properties including the capacity to cros...
Autores principales: | Frosina, Guido, Marubbi, Daniela, Marcello, Diana, Daga, Antonio |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6454723/ https://www.ncbi.nlm.nih.gov/pubmed/30961616 http://dx.doi.org/10.1186/s13014-019-1266-4 |
Ejemplares similares
-
ATR kinase inhibitors NVP-BEZ235 and AZD6738 effectively penetrate the brain after systemic administration
por: Fròsina, Guido, et al.
Publicado: (2018) -
Faithful animal modelling of human glioma by using primary initiating cells and its implications for radiosensitization therapy
por: Frosina, Guido, et al.
Publicado: (2018) -
Author Correction: Faithful animal modelling of human glioma by using primary initiating cells and its implications for radiosensitization therapy
por: Frosina, Guido, et al.
Publicado: (2019) -
Novel regulation of mitotic exit by the Cdc42 effectors Gic1 and Gic2
por: Höfken, Thomas, et al.
Publicado: (2004) -
A role for Gic1 and Gic2 in Cdc42 polarization at elevated temperature
por: Daniels, Christine N., et al.
Publicado: (2018)