Synovial tissue biopsy analysis: unlocking the hidden secrets to personalised medicine?

Rheumatoid arthritis is an immune-mediated inflammatory disease of the synovium. Yet we still lack robust tissue-specific (synovial) biomarkers that are able to guide clinical decisions and stratify patients according to their disease subgroup and predicted response to treatment. The EULAR Synovitis...

Descripción completa

Detalles Bibliográficos
Autor principal: McGettrick, Helen Michelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Editorial
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6454756/
https://www.ncbi.nlm.nih.gov/pubmed/30961644
http://dx.doi.org/10.1186/s13075-019-1871-5
Descripción
Sumario:Rheumatoid arthritis is an immune-mediated inflammatory disease of the synovium. Yet we still lack robust tissue-specific (synovial) biomarkers that are able to guide clinical decisions and stratify patients according to their disease subgroup and predicted response to treatment. The EULAR Synovitis Study Group and the OMERACT synovial tissue biopsy (STB) Special Interests Group have undertaken a consensus exercise to identify factors that are important for the standardisation of STB handling and analytical procedures in two situations—clinical practice and translational research.

Ejemplares similares