Synovial tissue biopsy analysis: unlocking the hidden secrets to personalised medicine?

Rheumatoid arthritis is an immune-mediated inflammatory disease of the synovium. Yet we still lack robust tissue-specific (synovial) biomarkers that are able to guide clinical decisions and stratify patients according to their disease subgroup and predicted response to treatment. The EULAR Synovitis...

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Autor principal: McGettrick, Helen Michelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Editorial
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6454756/
https://www.ncbi.nlm.nih.gov/pubmed/30961644
http://dx.doi.org/10.1186/s13075-019-1871-5
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author McGettrick, Helen Michelle
author_facet McGettrick, Helen Michelle
author_sort McGettrick, Helen Michelle
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description Rheumatoid arthritis is an immune-mediated inflammatory disease of the synovium. Yet we still lack robust tissue-specific (synovial) biomarkers that are able to guide clinical decisions and stratify patients according to their disease subgroup and predicted response to treatment. The EULAR Synovitis Study Group and the OMERACT synovial tissue biopsy (STB) Special Interests Group have undertaken a consensus exercise to identify factors that are important for the standardisation of STB handling and analytical procedures in two situations—clinical practice and translational research.
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spelling pubmed-64547562019-04-19 Synovial tissue biopsy analysis: unlocking the hidden secrets to personalised medicine? McGettrick, Helen Michelle Arthritis Res Ther Editorial Rheumatoid arthritis is an immune-mediated inflammatory disease of the synovium. Yet we still lack robust tissue-specific (synovial) biomarkers that are able to guide clinical decisions and stratify patients according to their disease subgroup and predicted response to treatment. The EULAR Synovitis Study Group and the OMERACT synovial tissue biopsy (STB) Special Interests Group have undertaken a consensus exercise to identify factors that are important for the standardisation of STB handling and analytical procedures in two situations—clinical practice and translational research. BioMed Central 2019-04-08 2019 /pmc/articles/PMC6454756/ /pubmed/30961644 http://dx.doi.org/10.1186/s13075-019-1871-5 Text en © The Author(s). 2019 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Editorial
McGettrick, Helen Michelle
Synovial tissue biopsy analysis: unlocking the hidden secrets to personalised medicine?
title Synovial tissue biopsy analysis: unlocking the hidden secrets to personalised medicine?
title_full Synovial tissue biopsy analysis: unlocking the hidden secrets to personalised medicine?
title_fullStr Synovial tissue biopsy analysis: unlocking the hidden secrets to personalised medicine?
title_full_unstemmed Synovial tissue biopsy analysis: unlocking the hidden secrets to personalised medicine?
title_short Synovial tissue biopsy analysis: unlocking the hidden secrets to personalised medicine?
title_sort synovial tissue biopsy analysis: unlocking the hidden secrets to personalised medicine?
topic Editorial
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6454756/
https://www.ncbi.nlm.nih.gov/pubmed/30961644
http://dx.doi.org/10.1186/s13075-019-1871-5
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