Systems biology based meth-miRNA–mRNA regulatory network identifies metabolic imbalance and hyperactive cell cycle signaling involved in hepatocellular carcinoma onset and progression

BACKGROUND: Hepatocellular carcinoma (HCC) is one of the leading cause of cancer associated deaths worldwide. Independent studies have proposed altered DNA methylation pattern and aberrant microRNA (miRNA) levels leading to abnormal expression of different genes as important regulators of disease on...

Descripción completa

Detalles Bibliográficos
Autores principales: Zahid, Kashif Rafiq, Su, Mingyang, Khan, Abdur Rehman Raza, Han, Shiming, Deming, Gou, Raza, Umar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Primary Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6454777/
https://www.ncbi.nlm.nih.gov/pubmed/31007607
http://dx.doi.org/10.1186/s12935-019-0804-3

Ejemplares similares

Ejemplares similares