Cargando…

Genome-Wide and Phenotypic Evaluation of Stem Cell Progenitors Derived From Gprc5a-Deficient Murine Lung Adenocarcinoma With Somatic Kras Mutations

Lung adenocarcinomas (LUADs) with somatic mutations in the KRAS oncogene comprise the most common molecular subtype of lung cancer in smokers and present with overall dismal prognosis and resistance to most therapies. Our group recently demonstrated that tobacco carcinogen-exposed mice with knockout...

Descripción completa

Detalles Bibliográficos
Autores principales:	Daouk, Reem, Hassane, Maya, Bahmad, Hisham F., Sinjab, Ansam, Fujimoto, Junya, Abou-Kheir, Wassim, Kadara, Humam
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6454871/ https://www.ncbi.nlm.nih.gov/pubmed/31001473 http://dx.doi.org/10.3389/fonc.2019.00207

Ejemplares similares

Genome-wide gene expression analysis of a murine model of prostate cancer progression: Deciphering the roles of IL-6 and p38 MAPK as potential therapeutic targets
por: Daouk, Reem, et al.
Publicado: (2020)

Anti-Tumor Effects of Biomimetic Sulfated Glycosaminoglycans on Lung Adenocarcinoma Cells in 2D and 3D In Vitro Models
por: Al Matari, Nada, et al.
Publicado: (2020)

Cell-by-Cell: Unlocking Lung Cancer Pathogenesis
por: Sinjab, Ansam, et al.
Publicado: (2022)

Comparative Functional Genomics Analysis of NNK Tobacco-Carcinogen Induced Lung Adenocarcinoma Development in Gprc5a-Knockout Mice
por: Fujimoto, Junya, et al.
Publicado: (2010)

Cancerona: Challenges of Cancer Management in Times of COVID-19 Pandemic
por: Ballout, Farah, et al.
Publicado: (2020)

Insights Into Lung Cancer Immune-Based Biology, Prevention, and Treatment
por: Saab, Sara, et al.
Publicado: (2020)

Smoking and Lung Cancer: A Geo-Regional Perspective
por: Rahal, Zahraa, et al.
Publicado: (2017)

Epigenetic Suppression of the T-box Subfamily 2 (TBX2) in Human Non-Small Cell Lung Cancer
por: Nehme, Eliana, et al.
Publicado: (2019)

Modeling Adipogenesis: Current and Future Perspective
por: Bahmad, Hisham F., et al.
Publicado: (2020)

Crosstalk between COVID-19 and prostate cancer
por: Bahmad, Hisham F., et al.
Publicado: (2020)

Prostate Cancer and Aspirin Use: Synopsis of the Proposed Molecular Mechanisms
por: Bilani, Nadeem, et al.
Publicado: (2017)

Pathogenesis of Tobacco-Associated Lung Adenocarcinoma Is Closely Coupled with Changes in the Gut and Lung Microbiomes
por: Finnicum, Casey T., et al.
Publicado: (2022)

Central nervous system tumors and three-dimensional cell biology: Current and future perspectives in modeling
por: Abou-Mrad, Zaki, et al.
Publicado: (2021)

Protein Expression Analysis of an In Vitro Murine Model of Prostate Cancer Progression: Towards Identification of High-Potential Therapeutic Targets
por: Bahmad, Hisham F., et al.
Publicado: (2020)

Epithelial-to-Mesenchymal Transition-Related Markers in Prostate Cancer: From Bench to Bedside
por: Gogola, Samantha, et al.
Publicado: (2023)

Cancer Stem Cells in Neuroblastoma: Expanding the Therapeutic Frontier
por: Bahmad, Hisham F., et al.
Publicado: (2019)

Metformin and Ara-a Effectively Suppress Brain Cancer by Targeting Cancer Stem/Progenitor Cells
por: Mouhieddine, Tarek H., et al.
Publicado: (2015)

Sphere-Formation Assay: Three-Dimensional in vitro Culturing of Prostate Cancer Stem/Progenitor Sphere-Forming Cells
por: Bahmad, Hisham F., et al.
Publicado: (2018)

The Akt/mTOR pathway in cancer stem/progenitor cells is a potential therapeutic target for glioblastoma and neuroblastoma
por: Bahmad, Hisham F., et al.
Publicado: (2018)

Primary versus castration-resistant prostate cancer: modeling through novel murine prostate cancer cell lines
por: Daoud, Georges, et al.
Publicado: (2016)

Modeling Human Neurological and Neurodegenerative Diseases: From Induced Pluripotent Stem Cells to Neuronal Differentiation and Its Applications in Neurotrauma
por: Bahmad, Hisham, et al.
Publicado: (2017)

Tumor Microenvironment in Prostate Cancer: Toward Identification of Novel Molecular Biomarkers for Diagnosis, Prognosis, and Therapy Development
por: Bahmad, Hisham F., et al.
Publicado: (2021)

Tissue-specific cancer stem/progenitor cells: Therapeutic implications
por: Yehya, Amani, et al.
Publicado: (2023)

The Use of Stem Cell-Derived Organoids in Disease Modeling: An Update
por: Azar, Joseph, et al.
Publicado: (2021)

LAPTM4B is associated with poor prognosis in NSCLC and promotes the NRF2-mediated stress response pathway in lung cancer cells
por: Maki, Yuho, et al.
Publicado: (2015)

Integrating whole transcriptome sequence data and public databases for analysis of somatic mutations in tumors
por: Momin, Amin A, et al.
Publicado: (2011)

Murine GPRC6A Mediates Cellular Responses to L-Amino Acids, but Not Osteocalcin Variants
por: Rueda, Patricia, et al.
Publicado: (2016)

Intranigral Injection of Endotoxin Suppresses Proliferation of Hippocampal Progenitor Cells
por: Darwish, Batoul, et al.
Publicado: (2019)

circGprc5a Promoted Bladder Oncogenesis and Metastasis through Gprc5a-Targeting Peptide
por: Gu, Chaohui, et al.
Publicado: (2018)

Epidermal Growth Factor Is Essential for the Maintenance of Novel Prostate Epithelial Cells Isolated From Patient-Derived Organoids
por: Cheaito, Katia, et al.
Publicado: (2020)

Nitrous Oxide Induces Prominent Cell Proliferation in Adult Rat Hippocampal Dentate Gyrus
por: Chamaa, Farah, et al.
Publicado: (2018)

The emerging roles of GPRC5A in diseases
por: Zhou, Honglei, et al.
Publicado: (2014)

Overcoming Drug Resistance in Advanced Prostate Cancer by Drug Repurposing
por: Bahmad, Hisham F., et al.
Publicado: (2022)

Transcriptomic Alterations in Lung Adenocarcinoma Unveil New Mechanisms Targeted by the TBX2 Subfamily of Tumor Suppressor Genes
por: Khalil, Athar, et al.
Publicado: (2018)

Immunohistochemical assessment of cannabinoid type-1 receptor (CB1R) and its correlation with clinicopathological parameters in glioma
por: Choucair, Nader, et al.
Publicado: (2022)

Assessing Radiosensitivity of Bladder Cancer in vitro: A 2D vs. 3D Approach
por: Bodgi, Larry, et al.
Publicado: (2019)

PTSD in the COVID-19 Era
por: Chamaa, Farah, et al.
Publicado: (2021)

Computationally identified novel agonists for GPRC6A
por: Pi, Min, et al.
Publicado: (2018)

GPRC5A: An Emerging Biomarker in Human Cancer
por: Jiang, Xiaoxia, et al.
Publicado: (2018)

Strategies for identification of somatic variants using the Ion Torrent deep targeted sequencing platform
por: Deshpande, Aditya, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_f8grqp7fp6h68k7jll3j6n7qbj