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Process standardization of Swarna Makshika Shodhana (purification) in Triphala Kwatha (decoction)

BACKGROUND: Swarna Makshika (SM) is a brassy golden yellowish mineral with chemical composition of CuFeS(2) that is widely used in therapeutics to treat various disease conditions such as Prameha (diabetes), Panḍu (anemia), Kushtha (skin diseases) and Jwara (fever). This mineral needs to be processe...

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Autores principales: Taviad, Krushn Kumar, Vekariya, Shweta, Bedarkar, Prashant, Galib, R., Patgiri, B. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6454905/
https://www.ncbi.nlm.nih.gov/pubmed/31000997
http://dx.doi.org/10.4103/ayu.AYU_26_18
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author Taviad, Krushn Kumar
Vekariya, Shweta
Bedarkar, Prashant
Galib, R.
Patgiri, B. J.
author_facet Taviad, Krushn Kumar
Vekariya, Shweta
Bedarkar, Prashant
Galib, R.
Patgiri, B. J.
author_sort Taviad, Krushn Kumar
collection PubMed
description BACKGROUND: Swarna Makshika (SM) is a brassy golden yellowish mineral with chemical composition of CuFeS(2) that is widely used in therapeutics to treat various disease conditions such as Prameha (diabetes), Panḍu (anemia), Kushtha (skin diseases) and Jwara (fever). This mineral needs to be processed by the following specified Ayurveda guidelines in order to make it therapeutically safe and more potent. These processes include Shodhana (preliminary process of eliminating unwanted substances), Marana (incineration) and Amritikarana (nectorization) that are mandatory and play a crucial role in therapeutics. However, till date, no published reports are available on standard manufacturing procedure of SM Shodhana. OBJECTIVE: The objective of this study is to develop the standard manufacturing procedure of SM Shodhana. MATERIALS AND METHODS: Methods described in Rasaratna Samuchhaya were followed to perform Shodhana process. Shodhana of SM was carried out in three batches (600 g in each batch) by seven quenching in Triphala Kwatha (TK, decoction of Terminalia chebula Retz., Terminalia bellirica Roxb. and Phyllanthus emblica Linn.) maintaining batch manufacturing records. Organoleptic and physicochemical analysis of media, i.e., TK and SM was carried out. RESULTS: After Shodhana, golden yellowish luster of SM was completely lost and it turned into dark black coarse powder. The hardness went on decreasing and brittleness went on increasing. Average 532 g of Shodhita SM (88.67%) from 600 g of SM was obtained. Average time required for achieving red hot stage was 24.81 min. Analysis of the media revealed an increase in pH, specific gravity, and total solid contents. CONCLUSION: The adopted method for Shodhana of 600 g of SM can be considered as easy, convenient and standard.
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spelling pubmed-64549052019-04-18 Process standardization of Swarna Makshika Shodhana (purification) in Triphala Kwatha (decoction) Taviad, Krushn Kumar Vekariya, Shweta Bedarkar, Prashant Galib, R. Patgiri, B. J. Ayu Pharmaceutical Study BACKGROUND: Swarna Makshika (SM) is a brassy golden yellowish mineral with chemical composition of CuFeS(2) that is widely used in therapeutics to treat various disease conditions such as Prameha (diabetes), Panḍu (anemia), Kushtha (skin diseases) and Jwara (fever). This mineral needs to be processed by the following specified Ayurveda guidelines in order to make it therapeutically safe and more potent. These processes include Shodhana (preliminary process of eliminating unwanted substances), Marana (incineration) and Amritikarana (nectorization) that are mandatory and play a crucial role in therapeutics. However, till date, no published reports are available on standard manufacturing procedure of SM Shodhana. OBJECTIVE: The objective of this study is to develop the standard manufacturing procedure of SM Shodhana. MATERIALS AND METHODS: Methods described in Rasaratna Samuchhaya were followed to perform Shodhana process. Shodhana of SM was carried out in three batches (600 g in each batch) by seven quenching in Triphala Kwatha (TK, decoction of Terminalia chebula Retz., Terminalia bellirica Roxb. and Phyllanthus emblica Linn.) maintaining batch manufacturing records. Organoleptic and physicochemical analysis of media, i.e., TK and SM was carried out. RESULTS: After Shodhana, golden yellowish luster of SM was completely lost and it turned into dark black coarse powder. The hardness went on decreasing and brittleness went on increasing. Average 532 g of Shodhita SM (88.67%) from 600 g of SM was obtained. Average time required for achieving red hot stage was 24.81 min. Analysis of the media revealed an increase in pH, specific gravity, and total solid contents. CONCLUSION: The adopted method for Shodhana of 600 g of SM can be considered as easy, convenient and standard. Wolters Kluwer - Medknow 2018 /pmc/articles/PMC6454905/ /pubmed/31000997 http://dx.doi.org/10.4103/ayu.AYU_26_18 Text en Copyright: © 2019 AYU (An International Quarterly Journal of Research in Ayurveda) http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Pharmaceutical Study
Taviad, Krushn Kumar
Vekariya, Shweta
Bedarkar, Prashant
Galib, R.
Patgiri, B. J.
Process standardization of Swarna Makshika Shodhana (purification) in Triphala Kwatha (decoction)
title Process standardization of Swarna Makshika Shodhana (purification) in Triphala Kwatha (decoction)
title_full Process standardization of Swarna Makshika Shodhana (purification) in Triphala Kwatha (decoction)
title_fullStr Process standardization of Swarna Makshika Shodhana (purification) in Triphala Kwatha (decoction)
title_full_unstemmed Process standardization of Swarna Makshika Shodhana (purification) in Triphala Kwatha (decoction)
title_short Process standardization of Swarna Makshika Shodhana (purification) in Triphala Kwatha (decoction)
title_sort process standardization of swarna makshika shodhana (purification) in triphala kwatha (decoction)
topic Pharmaceutical Study
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6454905/
https://www.ncbi.nlm.nih.gov/pubmed/31000997
http://dx.doi.org/10.4103/ayu.AYU_26_18
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