Transportan-derived cell-penetrating peptide delivers siRNA to inhibit replication of influenza virus in vivo

INTRODUCTION: In this study, we report on the development of an effective delivery system for siRNAs; a novel cell-penetrating peptide (CPP), T9(dR), obtained from transportan (TP), was used for in vivo and in vitro testing. METHODS: In this study, toxicity of T9(dR) and TP and efficient delivery of...

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Detalles Bibliográficos
Autores principales: Zhang, Cuiling, Ren, Weigang, Liu, Qingxin, Tan, Zhikai, Li, Junwei, Tong, Chunyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6454991/
https://www.ncbi.nlm.nih.gov/pubmed/31040643
http://dx.doi.org/10.2147/DDDT.S195481

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