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Nox2-dependent Neuroinflammation in An EAE Model of Multiple Sclerosis

BACKGROUND: Multiple sclerosis (MS) is an inflammatory disease of the CNS, characterized by demyelination, focal inflammatory infiltrates and axonal damage. Oxidative stress has been linked to MS pathology. Previous studies have suggested the involvement of NADPH oxidase 2 (Nox2), an enzyme that cat...

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Detalles Bibliográficos
Autores principales: Ravelli, Katherine G., Santos, Graziella D., dos Santos, Nilton B., Munhoz, Carolina D., Azzi-Nogueira, Deborah, Campos, Ana Carolina, Pagano, Rosana L., Britto, Luiz R., Hernandes, Marina S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: De Gruyter 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6455010/
https://www.ncbi.nlm.nih.gov/pubmed/30984416
http://dx.doi.org/10.1515/tnsci-2019-0001