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Evaluation of in vitro Assays to Assess the Modulation of Dendritic Cells Functions by Therapeutic Antibodies and Aggregates

Therapeutic antibodies have the potential to induce immunogenicity leading to the development of anti-drug antibodies (ADA) that consequently may result in reduced serum drug concentrations, a loss of efficacy or potential hypersensitivity reactions. Among other factors, aggregated antibodies have b...

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Detalles Bibliográficos
Autores principales:	Morgan, Hannah, Tseng, Su-Yi, Gallais, Yann, Leineweber, Margret, Buchmann, Pascale, Riccardi, Sabrina, Nabhan, Myriam, Lo, Jeannette, Gani, Zaahira, Szely, Natacha, Zhu, Cornelia S., Yang, Ming, Kiessling, Andrea, Vohr, Hans-Werner, Pallardy, Marc, Aswad, Fred, Turbica, Isabelle
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6455063/ https://www.ncbi.nlm.nih.gov/pubmed/31001248 http://dx.doi.org/10.3389/fimmu.2019.00601

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