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Computed tomography scan contribution to the diagnosis of community-acquired pneumonia
PURPOSE OF REVIEW: Pneumonia is a frequent disease mainly affecting older and multimorbid patients. Symptoms and signs lack sensitivity and specificity, and chest X-ray has poor accuracy. Hence, an initial diagnosis of pneumonia has limited predictive value for the presence of pneumonia. Overdiagnos...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6455090/ https://www.ncbi.nlm.nih.gov/pubmed/30730311 http://dx.doi.org/10.1097/MCP.0000000000000567 |
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author | Garin, Nicolas Marti, Christophe Scheffler, Max Stirnemann, Jérôme Prendki, Virginie |
author_facet | Garin, Nicolas Marti, Christophe Scheffler, Max Stirnemann, Jérôme Prendki, Virginie |
author_sort | Garin, Nicolas |
collection | PubMed |
description | PURPOSE OF REVIEW: Pneumonia is a frequent disease mainly affecting older and multimorbid patients. Symptoms and signs lack sensitivity and specificity, and chest X-ray has poor accuracy. Hence, an initial diagnosis of pneumonia has limited predictive value for the presence of pneumonia. Overdiagnosis of pneumonia leads to inappropriate antibiotic use and may delay the appropriate management of mimicking diseases. Alternative imaging strategies including computed tomography (CT)-scan or lung ultrasonography may improve the diagnosis of pneumonia. We review the recent evidence and perspectives regarding their contribution to the diagnosis and management of patients with suspected pneumonia. RECENT FINDINGS: Two studies assessed the diagnostic accuracy of CT-scan in emergency department or hospitalized patients suspected of pneumonia. CT-scan led to a net reclassification improvement of 8 and 18% of patients, and was particularly helpful to rule out the diagnosis, allowing a lowering of the number of inappropriate antibiotic prescriptions. SUMMARY: CT-scan reduces overdiagnosis of pneumonia and allows a better identification of alternative diagnoses. The impact on clinical outcomes of a strategy incorporating CT-scan for patients suspected of pneumonia should be evaluated, along with its cost-effectiveness. |
format | Online Article Text |
id | pubmed-6455090 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Lippincott Williams & Wilkins |
record_format | MEDLINE/PubMed |
spelling | pubmed-64550902019-05-01 Computed tomography scan contribution to the diagnosis of community-acquired pneumonia Garin, Nicolas Marti, Christophe Scheffler, Max Stirnemann, Jérôme Prendki, Virginie Curr Opin Pulm Med INFECTIOUS DISEASES: Edited by Michael S. Niederman and Alimuddin Zumla PURPOSE OF REVIEW: Pneumonia is a frequent disease mainly affecting older and multimorbid patients. Symptoms and signs lack sensitivity and specificity, and chest X-ray has poor accuracy. Hence, an initial diagnosis of pneumonia has limited predictive value for the presence of pneumonia. Overdiagnosis of pneumonia leads to inappropriate antibiotic use and may delay the appropriate management of mimicking diseases. Alternative imaging strategies including computed tomography (CT)-scan or lung ultrasonography may improve the diagnosis of pneumonia. We review the recent evidence and perspectives regarding their contribution to the diagnosis and management of patients with suspected pneumonia. RECENT FINDINGS: Two studies assessed the diagnostic accuracy of CT-scan in emergency department or hospitalized patients suspected of pneumonia. CT-scan led to a net reclassification improvement of 8 and 18% of patients, and was particularly helpful to rule out the diagnosis, allowing a lowering of the number of inappropriate antibiotic prescriptions. SUMMARY: CT-scan reduces overdiagnosis of pneumonia and allows a better identification of alternative diagnoses. The impact on clinical outcomes of a strategy incorporating CT-scan for patients suspected of pneumonia should be evaluated, along with its cost-effectiveness. Lippincott Williams & Wilkins 2019-05 2019-02-05 /pmc/articles/PMC6455090/ /pubmed/30730311 http://dx.doi.org/10.1097/MCP.0000000000000567 Text en Copyright © 2019 The Author(s). Published by Wolters Kluwer Health, Inc. http://creativecommons.org/licenses/by-nc-nd/4.0 This is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal. http://creativecommons.org/licenses/by-nc-nd/4.0 |
spellingShingle | INFECTIOUS DISEASES: Edited by Michael S. Niederman and Alimuddin Zumla Garin, Nicolas Marti, Christophe Scheffler, Max Stirnemann, Jérôme Prendki, Virginie Computed tomography scan contribution to the diagnosis of community-acquired pneumonia |
title | Computed tomography scan contribution to the diagnosis of community-acquired pneumonia |
title_full | Computed tomography scan contribution to the diagnosis of community-acquired pneumonia |
title_fullStr | Computed tomography scan contribution to the diagnosis of community-acquired pneumonia |
title_full_unstemmed | Computed tomography scan contribution to the diagnosis of community-acquired pneumonia |
title_short | Computed tomography scan contribution to the diagnosis of community-acquired pneumonia |
title_sort | computed tomography scan contribution to the diagnosis of community-acquired pneumonia |
topic | INFECTIOUS DISEASES: Edited by Michael S. Niederman and Alimuddin Zumla |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6455090/ https://www.ncbi.nlm.nih.gov/pubmed/30730311 http://dx.doi.org/10.1097/MCP.0000000000000567 |
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