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Computed tomography scan contribution to the diagnosis of community-acquired pneumonia

PURPOSE OF REVIEW: Pneumonia is a frequent disease mainly affecting older and multimorbid patients. Symptoms and signs lack sensitivity and specificity, and chest X-ray has poor accuracy. Hence, an initial diagnosis of pneumonia has limited predictive value for the presence of pneumonia. Overdiagnos...

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Autores principales: Garin, Nicolas, Marti, Christophe, Scheffler, Max, Stirnemann, Jérôme, Prendki, Virginie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6455090/
https://www.ncbi.nlm.nih.gov/pubmed/30730311
http://dx.doi.org/10.1097/MCP.0000000000000567
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author Garin, Nicolas
Marti, Christophe
Scheffler, Max
Stirnemann, Jérôme
Prendki, Virginie
author_facet Garin, Nicolas
Marti, Christophe
Scheffler, Max
Stirnemann, Jérôme
Prendki, Virginie
author_sort Garin, Nicolas
collection PubMed
description PURPOSE OF REVIEW: Pneumonia is a frequent disease mainly affecting older and multimorbid patients. Symptoms and signs lack sensitivity and specificity, and chest X-ray has poor accuracy. Hence, an initial diagnosis of pneumonia has limited predictive value for the presence of pneumonia. Overdiagnosis of pneumonia leads to inappropriate antibiotic use and may delay the appropriate management of mimicking diseases. Alternative imaging strategies including computed tomography (CT)-scan or lung ultrasonography may improve the diagnosis of pneumonia. We review the recent evidence and perspectives regarding their contribution to the diagnosis and management of patients with suspected pneumonia. RECENT FINDINGS: Two studies assessed the diagnostic accuracy of CT-scan in emergency department or hospitalized patients suspected of pneumonia. CT-scan led to a net reclassification improvement of 8 and 18% of patients, and was particularly helpful to rule out the diagnosis, allowing a lowering of the number of inappropriate antibiotic prescriptions. SUMMARY: CT-scan reduces overdiagnosis of pneumonia and allows a better identification of alternative diagnoses. The impact on clinical outcomes of a strategy incorporating CT-scan for patients suspected of pneumonia should be evaluated, along with its cost-effectiveness.
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spelling pubmed-64550902019-05-01 Computed tomography scan contribution to the diagnosis of community-acquired pneumonia Garin, Nicolas Marti, Christophe Scheffler, Max Stirnemann, Jérôme Prendki, Virginie Curr Opin Pulm Med INFECTIOUS DISEASES: Edited by Michael S. Niederman and Alimuddin Zumla PURPOSE OF REVIEW: Pneumonia is a frequent disease mainly affecting older and multimorbid patients. Symptoms and signs lack sensitivity and specificity, and chest X-ray has poor accuracy. Hence, an initial diagnosis of pneumonia has limited predictive value for the presence of pneumonia. Overdiagnosis of pneumonia leads to inappropriate antibiotic use and may delay the appropriate management of mimicking diseases. Alternative imaging strategies including computed tomography (CT)-scan or lung ultrasonography may improve the diagnosis of pneumonia. We review the recent evidence and perspectives regarding their contribution to the diagnosis and management of patients with suspected pneumonia. RECENT FINDINGS: Two studies assessed the diagnostic accuracy of CT-scan in emergency department or hospitalized patients suspected of pneumonia. CT-scan led to a net reclassification improvement of 8 and 18% of patients, and was particularly helpful to rule out the diagnosis, allowing a lowering of the number of inappropriate antibiotic prescriptions. SUMMARY: CT-scan reduces overdiagnosis of pneumonia and allows a better identification of alternative diagnoses. The impact on clinical outcomes of a strategy incorporating CT-scan for patients suspected of pneumonia should be evaluated, along with its cost-effectiveness. Lippincott Williams & Wilkins 2019-05 2019-02-05 /pmc/articles/PMC6455090/ /pubmed/30730311 http://dx.doi.org/10.1097/MCP.0000000000000567 Text en Copyright © 2019 The Author(s). Published by Wolters Kluwer Health, Inc. http://creativecommons.org/licenses/by-nc-nd/4.0 This is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal. http://creativecommons.org/licenses/by-nc-nd/4.0
spellingShingle INFECTIOUS DISEASES: Edited by Michael S. Niederman and Alimuddin Zumla
Garin, Nicolas
Marti, Christophe
Scheffler, Max
Stirnemann, Jérôme
Prendki, Virginie
Computed tomography scan contribution to the diagnosis of community-acquired pneumonia
title Computed tomography scan contribution to the diagnosis of community-acquired pneumonia
title_full Computed tomography scan contribution to the diagnosis of community-acquired pneumonia
title_fullStr Computed tomography scan contribution to the diagnosis of community-acquired pneumonia
title_full_unstemmed Computed tomography scan contribution to the diagnosis of community-acquired pneumonia
title_short Computed tomography scan contribution to the diagnosis of community-acquired pneumonia
title_sort computed tomography scan contribution to the diagnosis of community-acquired pneumonia
topic INFECTIOUS DISEASES: Edited by Michael S. Niederman and Alimuddin Zumla
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6455090/
https://www.ncbi.nlm.nih.gov/pubmed/30730311
http://dx.doi.org/10.1097/MCP.0000000000000567
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