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Human MxA is a potent interspecies barrier for the novel bat-derived influenza A-like virus H18N11

The human innate immune factor MxA represents an effective interspecies barrier for zoonotic influenza A viruses (IAVs) of animal origin. Accordingly, human but not avian IAVs efficiently escape the antiviral activity of MxA due to adaptive mutations in their viral nucleoprotein. Partial MxA resista...

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Detalles Bibliográficos
Autores principales:	Ciminski, Kevin, Pulvermüller, Johanna, Adam, Julia, Schwemmle, Martin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6455144/ https://www.ncbi.nlm.nih.gov/pubmed/30945621 http://dx.doi.org/10.1080/22221751.2019.1599301

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