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Targeting Tumor Vascular CD99 Inhibits Tumor Growth
CD99 (MIC2; single-chain type-1 glycoprotein) is a heavily O-glycosylated transmembrane protein (32 kDa) present on leukocytes and activated endothelium. Expression of CD99 on endothelium is important in lymphocyte diapedesis. CD99 is a diagnostic marker for Ewing's Sarcoma (EWS), as it is high...
Autores principales: | Huijbers, Elisabeth J. M., van der Werf, Inge M., Faber, Lisette D., Sialino, Lena D., van der Laan, Pia, Holland, Hanna A., Cimpean, Anca M., Thijssen, Victor L. J. L., van Beijnum, Judy R., Griffioen, Arjan W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6455290/ https://www.ncbi.nlm.nih.gov/pubmed/31001265 http://dx.doi.org/10.3389/fimmu.2019.00651 |
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