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Sez6 levels are elevated in cerebrospinal fluid of patients with inflammatory pain–associated conditions
INTRODUCTION: Seizure-related protein 6 (Sez6) contributes to chronic pain development as sez6 knockout mice show attenuated pain behaviours after peripheral nerve injury, compared with control mice. The type I transmembrane isoform of Sez6 is cleaved by the β-amyloid precursor protein cleavage enzy...
Autores principales: | Roitman, Maria, Edgington-Mitchell, Laura E., Mangum, Jon, Ziogas, James, Adamides, Alexios A., Myles, Paul, Choo-Bunnett, Hearan, Bunnett, Nigel W., Gunnersen, Jenny M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6455686/ https://www.ncbi.nlm.nih.gov/pubmed/31041421 http://dx.doi.org/10.1097/PR9.0000000000000719 |
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