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Sez6 levels are elevated in cerebrospinal fluid of patients with inflammatory pain–associated conditions

INTRODUCTION: Seizure-related protein 6 (Sez6) contributes to chronic pain development as sez6 knockout mice show attenuated pain behaviours after peripheral nerve injury, compared with control mice. The type I transmembrane isoform of Sez6 is cleaved by the β-amyloid precursor protein cleavage enzy...

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Detalles Bibliográficos
Autores principales: Roitman, Maria, Edgington-Mitchell, Laura E., Mangum, Jon, Ziogas, James, Adamides, Alexios A., Myles, Paul, Choo-Bunnett, Hearan, Bunnett, Nigel W., Gunnersen, Jenny M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6455686/
https://www.ncbi.nlm.nih.gov/pubmed/31041421
http://dx.doi.org/10.1097/PR9.0000000000000719

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