Cargando…
The Association between Dietary Fat Pattern and the Risk of Type 2 Diabetes
Despite several studies examining single dietary fats on type 2 diabetes (T2D) incidence, little is known about the effects of multiple fatty acids on the risk of T2D. We aimed to address this question in the Tehran Lipid and Glucose Study (TLGS) population. Dietary intakes of participants without T...
Autores principales: | , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Korean Society of Food Science and Nutrition
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6456237/ https://www.ncbi.nlm.nih.gov/pubmed/31008091 http://dx.doi.org/10.3746/pnf.2019.24.1.1 |
_version_ | 1783409737819226112 |
---|---|
author | Gaeini, Zahra Bahadoran, Zahra Mirmiran, Parvin Djazayery, Abolghasem |
author_facet | Gaeini, Zahra Bahadoran, Zahra Mirmiran, Parvin Djazayery, Abolghasem |
author_sort | Gaeini, Zahra |
collection | PubMed |
description | Despite several studies examining single dietary fats on type 2 diabetes (T2D) incidence, little is known about the effects of multiple fatty acids on the risk of T2D. We aimed to address this question in the Tehran Lipid and Glucose Study (TLGS) population. Dietary intakes of participants without T2D (n=2,139) were assessed using the validated food frequency questionnaire. To assess the risk of T2D after 6 years of follow-up, we used multivariate Cox proportional hazard regression models. Three major dietary fat patterns were: (1) high amounts of dietary cholesterol, saturated fats, oleic acid, linoleic acid, linolenic acid, and trans fats; (2) high amounts of long-chain polyunsaturated fats; and (3) high amounts of dietary cholesterol and saturated fats. Dietary total fat intake hazard ratio [HR=1.31, 95% confidence interval (CI)=0.77~2.23 and HR=0.69, 95% CI=0.27~1.76, in the second and third tertile, respectively] was not related to the development of T2D. Animal- and plant-based dietary fat intakes were additionally not related to the risk of T2D. After adjustment for confounding variables, there was no significant association between dietary fat pattern score and T2D incidence. Whereas, the third pattern had a borderline negative association with diabetes development (HR=0.56, 95% CI=0.29~1.07). These novel data suggest that dietary fat composition may modify the risk of T2D incidence. |
format | Online Article Text |
id | pubmed-6456237 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | The Korean Society of Food Science and Nutrition |
record_format | MEDLINE/PubMed |
spelling | pubmed-64562372019-04-19 The Association between Dietary Fat Pattern and the Risk of Type 2 Diabetes Gaeini, Zahra Bahadoran, Zahra Mirmiran, Parvin Djazayery, Abolghasem Prev Nutr Food Sci Articles Despite several studies examining single dietary fats on type 2 diabetes (T2D) incidence, little is known about the effects of multiple fatty acids on the risk of T2D. We aimed to address this question in the Tehran Lipid and Glucose Study (TLGS) population. Dietary intakes of participants without T2D (n=2,139) were assessed using the validated food frequency questionnaire. To assess the risk of T2D after 6 years of follow-up, we used multivariate Cox proportional hazard regression models. Three major dietary fat patterns were: (1) high amounts of dietary cholesterol, saturated fats, oleic acid, linoleic acid, linolenic acid, and trans fats; (2) high amounts of long-chain polyunsaturated fats; and (3) high amounts of dietary cholesterol and saturated fats. Dietary total fat intake hazard ratio [HR=1.31, 95% confidence interval (CI)=0.77~2.23 and HR=0.69, 95% CI=0.27~1.76, in the second and third tertile, respectively] was not related to the development of T2D. Animal- and plant-based dietary fat intakes were additionally not related to the risk of T2D. After adjustment for confounding variables, there was no significant association between dietary fat pattern score and T2D incidence. Whereas, the third pattern had a borderline negative association with diabetes development (HR=0.56, 95% CI=0.29~1.07). These novel data suggest that dietary fat composition may modify the risk of T2D incidence. The Korean Society of Food Science and Nutrition 2019-03 2019-03-31 /pmc/articles/PMC6456237/ /pubmed/31008091 http://dx.doi.org/10.3746/pnf.2019.24.1.1 Text en Copyright © 2019 by The Korean Society of Food Science and Nutrition This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Articles Gaeini, Zahra Bahadoran, Zahra Mirmiran, Parvin Djazayery, Abolghasem The Association between Dietary Fat Pattern and the Risk of Type 2 Diabetes |
title | The Association between Dietary Fat Pattern and the Risk of Type 2 Diabetes |
title_full | The Association between Dietary Fat Pattern and the Risk of Type 2 Diabetes |
title_fullStr | The Association between Dietary Fat Pattern and the Risk of Type 2 Diabetes |
title_full_unstemmed | The Association between Dietary Fat Pattern and the Risk of Type 2 Diabetes |
title_short | The Association between Dietary Fat Pattern and the Risk of Type 2 Diabetes |
title_sort | association between dietary fat pattern and the risk of type 2 diabetes |
topic | Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6456237/ https://www.ncbi.nlm.nih.gov/pubmed/31008091 http://dx.doi.org/10.3746/pnf.2019.24.1.1 |
work_keys_str_mv | AT gaeinizahra theassociationbetweendietaryfatpatternandtheriskoftype2diabetes AT bahadoranzahra theassociationbetweendietaryfatpatternandtheriskoftype2diabetes AT mirmiranparvin theassociationbetweendietaryfatpatternandtheriskoftype2diabetes AT djazayeryabolghasem theassociationbetweendietaryfatpatternandtheriskoftype2diabetes AT gaeinizahra associationbetweendietaryfatpatternandtheriskoftype2diabetes AT bahadoranzahra associationbetweendietaryfatpatternandtheriskoftype2diabetes AT mirmiranparvin associationbetweendietaryfatpatternandtheriskoftype2diabetes AT djazayeryabolghasem associationbetweendietaryfatpatternandtheriskoftype2diabetes |