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Intergenerational epigenetic inheritance of cancer susceptibility in mammals

Susceptibility to cancer is heritable, but much of this heritability remains unexplained. Some ‘missing’ heritability may be mediated by epigenetic changes in the parental germ line that do not involve transmission of genetic variants from parent to offspring. We report that deletion of the chromati...

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Detalles Bibliográficos
Autores principales:	Lesch, Bluma J, Tothova, Zuzana, Morgan, Elizabeth A, Liao, Zhicong, Bronson, Roderick T, Ebert, Benjamin L, Page, David C
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2019
Materias:	Chromosomes and Gene Expression
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6456297/ https://www.ncbi.nlm.nih.gov/pubmed/30963999 http://dx.doi.org/10.7554/eLife.39380

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