Cargando…

Effect of a High-Fat Diet and Metformin on Placental mTOR Signaling in Mice

Objective This study was aimed to measure the effects of a high-fat diet and metformin on placental mechanistic target of rapamycin (mTOR) signaling in mice. Study Design Pregnant friend virus B (FVB)-strain mice were allocated on embryonic day (e) 0.5 to one of four groups; group 1: control diet...

Descripción completa

Detalles Bibliográficos
Autores principales:	Grace, Matthew R., Dotters-Katz, Sarah K., Zhou, Chunxiao, Manuck, Tracy, Boggess, Kim, Bae-Jump, Victoria
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Thieme Medical Publishers 2019
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6456331/ https://www.ncbi.nlm.nih.gov/pubmed/30972229 http://dx.doi.org/10.1055/s-0039-1683362

Ejemplares similares

Prophylactic Antibiotics in Twin Pregnancies Complicated by Previable Preterm Premature Rupture of Membranes
por: Myrick, Olivia, et al.
Publicado: (2016)

Diet‐induced obesity in mice reduces placental efficiency and inhibits placental mTOR signaling
por: Lager, Susanne, et al.
Publicado: (2014)

Glutamine promotes ovarian cancer cell proliferation through the mTOR/S6 pathway
por: Yuan, Lingqin, et al.
Publicado: (2015)

SPR965, a Dual PI3K/mTOR Inhibitor, as a Targeted Therapy in Ovarian Cancer
por: Tran, Arthur-Quan, et al.
Publicado: (2021)

Effects of treadmill exercise on skeletal muscle mTOR signaling pathway in high-fat diet-induced obese mice
por: Woo, Jin Hee, et al.
Publicado: (2016)

Impact of placental mTOR deficiency on peripheral insulin signaling in adult mice offspring
por: Beetch, Megan, et al.
Publicado: (2023)

Metformin induces degradation of mTOR protein in breast cancer cells
por: Alalem, Mohamed, et al.
Publicado: (2016)

Inhibition of placental mTOR signaling provides a link between placental malaria and reduced birthweight
por: Dimasuay, Kris Genelyn, et al.
Publicado: (2017)

Placental mTOR complex 1 regulates fetal programming of obesity and insulin resistance in mice
por: Akhaphong, Brian, et al.
Publicado: (2021)

Tadalafil Treatment of Mice with Fetal Growth Restriction and Preeclampsia Improves Placental mTOR Signaling
por: Tanaka, Kayo, et al.
Publicado: (2022)

Oleic Acid Exhibits Anti-Proliferative and Anti-Invasive Activities via the PTEN/AKT/mTOR Pathway in Endometrial Cancer
por: Deng, Boer, et al.
Publicado: (2023)

Inhibition of mTOR signaling and clinical activity of metformin in oral premalignant lesions
por: Gutkind, J. Silvio, et al.
Publicado: (2021)

Placental mTOR Signaling and Sexual Dimorphism in Metabolic Health across the Lifespan of Offspring
por: Beetch, Megan, et al.
Publicado: (2021)

Exercise and dietary change ameliorate high fat diet induced obesity and insulin resistance via mTOR signaling pathway
por: Bae, Ju Yong, et al.
Publicado: (2016)

mTOR Pathway and mTOR Inhibitors in Head and Neck Cancer
por: Gao, Wei, et al.
Publicado: (2012)

The Synergistic Effect of an ATP-Competitive Inhibitor of mTOR and Metformin on Pancreatic Tumor Growth
por: Soliman, Ghada A, et al.
Publicado: (2020)

Metformin attenuates cartilage degeneration in an experimental osteoarthritis model by regulating AMPK/mTOR
por: Feng, Xiaofeng, et al.
Publicado: (2020)

Myelination and mTOR
por: Figlia, Gianluca, et al.
Publicado: (2017)

mTOR signaling pathway and mTOR inhibitors in cancer: progress and challenges
por: Zou, Zhilin, et al.
Publicado: (2020)

Metformin sensitizes chemotherapy by targeting cancer stem cells and the mTOR pathway in esophageal cancer
por: HONJO, SOICHIRO, et al.
Publicado: (2014)

Metformin and Dichloroacetate Suppress Proliferation of Liver Cancer Cells by Inhibiting mTOR Complex 1
por: Kim, Tae Suk, et al.
Publicado: (2021)

Immunomodulatory and Antiaging Mechanisms of Resveratrol, Rapamycin, and Metformin: Focus on mTOR and AMPK Signaling Networks
por: Sorrenti, Vincenzo, et al.
Publicado: (2022)

mTOR Signaling in Cancer and mTOR Inhibitors in Solid Tumor Targeting Therapy
por: Tian, Tian, et al.
Publicado: (2019)

Regulation of Osteoclast Growth and Fusion by mTOR/raptor and mTOR/rictor/Akt
por: Tiedemann, Kerstin, et al.
Publicado: (2017)

Escaping mTOR inhibition for cancer therapy: Tumor suppressor functions of mTOR
por: Villar, Victor H., et al.
Publicado: (2017)

Overcoming mTOR Resistance Mutations with a New Generation mTOR Inhibitor
por: Rodrik-Outmezguine, Vanessa S., et al.
Publicado: (2016)

SUN-635 Profiling of Activation Patterns of Placental mTOR in Pregnancies Complicated by Gestational Diabetes Mellitus
por: Papadopoulou, Anna, et al.
Publicado: (2020)

mTOR and lysosome regulation
por: Puertollano, Rosa
Publicado: (2014)

mTOR, autophagy, and reprogramming
por: Tang, Bor Luen
Publicado: (2014)

Targeting glutaminase and mTOR
por: Tanaka, Kazuhiro, et al.
Publicado: (2015)

mTOR in cerebrovascular disease
por: Van Skike, Candice E., et al.
Publicado: (2019)

mTOR and Tumor Cachexia
por: Duval, Adrian P., et al.
Publicado: (2018)

Double agent mTOR
por: Danzer, Steve C.
Publicado: (2019)

mTOR in Human Diseases
por: Dormond, Olivier
Publicado: (2019)

Chronic Repression of mTOR Complex 2 Induces Changes in the Gut Microbiota of Diet-induced Obese Mice
por: Jung, Mi-Ja, et al.
Publicado: (2016)

Commentary: Overcoming mTOR resistance mutations with a new-generation mTOR inhibitor
por: Renna, Maurizio
Publicado: (2016)

Metformin Inhibits the NLRP3 Inflammasome via AMPK/mTOR-dependent Effects in Diabetic Cardiomyopathy
por: Yang, Fan, et al.
Publicado: (2019)

Metformin Induces Autophagy via the AMPK-mTOR Signaling Pathway in Human Hepatocellular Carcinoma Cells
por: Gao, Chun, et al.
Publicado: (2020)

Metformin Potentiates the Effects of Anlotinib in NSCLC via AMPK/mTOR and ROS-Mediated Signaling Pathways
por: Zhu, Zhongling, et al.
Publicado: (2021)

Metformin enhances anti-cancer effects of cisplatin in meningioma through AMPK-mTOR signaling pathways
por: Guo, Liemei, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_da9gl4ik2ahfvsphc9019ltg1s