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Acquired von Willebrand Syndrome Associated with Cardiovascular Diseases

The blood glycoprotein von Willebrand factor (VWF) plays an important role in hemostasis and thrombosis. VWF is produced and secreted as large multimers by endothelial cells and megakaryocytes. It is then cleaved in a sheer-stress dependent manner by a specific protease, ADAMTS13, into multimers con...

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Detalles Bibliográficos
Autores principales: Horiuchi, Hisanori, Doman, Tsuyoshi, Kokame, Koichi, Saiki, Yoshikatsu, Matsumoto, Masanori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japan Atherosclerosis Society 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6456452/
https://www.ncbi.nlm.nih.gov/pubmed/30867356
http://dx.doi.org/10.5551/jat.RV17031