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The free energy landscape of the oncogene protein E7 of human papillomavirus type 16 reveals a complex interplay between ordered and disordered regions
When present, structural disorder makes it very challenging to characterise the conformational properties of proteins. This is particularly the case of proteins, such as the oncogene protein E7 of human papillomavirus type 16, which contain both ordered and disordered domains, and that can populate...
Autores principales: | Kukic, Predrag, Lo Piccolo, Giuseppe Mattia, Nogueira, Marcela O., Svergun, Dmitri I., Vendruscolo, Michele, Felli, Isabella C., Pierattelli, Roberta |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6456579/ https://www.ncbi.nlm.nih.gov/pubmed/30967564 http://dx.doi.org/10.1038/s41598-019-41925-4 |
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