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Efficient allelic-drive in Drosophila
Gene-drive systems developed in several organisms result in super-Mendelian inheritance of transgenic insertions. Here, we generalize this “active genetic” approach to preferentially transmit allelic variants (allelic-drive) resulting from only a single or a few nucleotide alterations. We test two c...
Autores principales: | Guichard, Annabel, Haque, Tisha, Bobik, Marketta, Xu, Xiang-Ru S., Klanseck, Carissa, Kushwah, Raja Babu Singh, Berni, Mateus, Kaduskar, Bhagyashree, Gantz, Valentino M., Bier, Ethan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6456580/ https://www.ncbi.nlm.nih.gov/pubmed/30967548 http://dx.doi.org/10.1038/s41467-019-09694-w |
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