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Global identification of functional microRNA-mRNA interactions in Drosophila

MicroRNAs (miRNAs) are key mediators of post-transcriptional gene expression silencing. So far, no comprehensive experimental annotation of functional miRNA target sites exists in Drosophila. Here, we generated a transcriptome-wide in vivo map of miRNA-mRNA interactions in Drosophila melanogaster, m...

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Detalles Bibliográficos
Autores principales: Wessels, Hans-Hermann, Lebedeva, Svetlana, Hirsekorn, Antje, Wurmus, Ricardo, Akalin, Altuna, Mukherjee, Neelanjan, Ohler, Uwe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6456604/
https://www.ncbi.nlm.nih.gov/pubmed/30967537
http://dx.doi.org/10.1038/s41467-019-09586-z