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Accuracy of Gene Expression Prediction From Genotype Data With PrediXcan Varies Across and Within Continental Populations

Using genetic data to predict gene expression has garnered significant attention in recent years. PrediXcan has become one of the most widely used gene-based methods for testing associations between predicted gene expression values and a phenotype, which has facilitated novel insights into the relat...

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Detalles Bibliográficos
Autores principales: Mikhaylova, Anna V., Thornton, Timothy A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6456650/
https://www.ncbi.nlm.nih.gov/pubmed/31001318
http://dx.doi.org/10.3389/fgene.2019.00261