Antiproliferative Effects of the Natural Oxadiazine Nocuolin A Are Associated With Impairment of Mitochondrial Oxidative Phosphorylation

Natural products are interesting sources for drug discovery. The natural product oxadiazine Nocuolin A (NocA) was previously isolated from the cyanobacterial strain Nodularia sp. LEGE 06071 and here we examined its cytotoxic effects against different strains of the colon cancer cell line HCT116 and...

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Detalles Bibliográficos
Autores principales: Sousa, Maria Lígia, Preto, Marco, Vasconcelos, Vítor, Linder, Stig, Urbatzka, Ralph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6456697/
https://www.ncbi.nlm.nih.gov/pubmed/31001482
http://dx.doi.org/10.3389/fonc.2019.00224

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6456697/
https://www.ncbi.nlm.nih.gov/pubmed/31001482
http://dx.doi.org/10.3389/fonc.2019.00224

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