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Antiproliferative Effects of the Natural Oxadiazine Nocuolin A Are Associated With Impairment of Mitochondrial Oxidative Phosphorylation
Natural products are interesting sources for drug discovery. The natural product oxadiazine Nocuolin A (NocA) was previously isolated from the cyanobacterial strain Nodularia sp. LEGE 06071 and here we examined its cytotoxic effects against different strains of the colon cancer cell line HCT116 and...
Autores principales: | Sousa, Maria Lígia, Preto, Marco, Vasconcelos, Vítor, Linder, Stig, Urbatzka, Ralph |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6456697/ https://www.ncbi.nlm.nih.gov/pubmed/31001482 http://dx.doi.org/10.3389/fonc.2019.00224 |
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