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NCS-1 Deficiency Is Associated With Obesity and Diabetes Type 2 in Mice

Neuronal calcium sensor-1 (NCS-1) knockout (KO) in mice (NCS-1(−/−) mice) evokes behavioral phenotypes ranging from learning deficits to avolition and depressive-like behaviors. Here, we showed that with the onset of adulthood NCS-1(−/−) mice gain considerable weight. Adult NCS-1(−/−) mice are obese...

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Detalles Bibliográficos
Autores principales: Ratai, Olga, Hermainski, Joanna, Ravichandran, Keerthana, Pongs, Olaf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6456702/
https://www.ncbi.nlm.nih.gov/pubmed/31001084
http://dx.doi.org/10.3389/fnmol.2019.00078