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Medroxyprogesterone Acetate Decreases Th1, Th17, and Increases Th22 Responses via AHR Signaling Which Could Affect Susceptibility to Infections and Inflammatory Disease
A synthetic progestin, medroxyprogesterone acetate (MPA), was used in a novel study to determine progestin effects on human purified macrophages and Th1, Th2, Th17, Th22 cells. MPA concentrations were equivalent to those in the serum of women after 6 and 9 months of progestin use. MPA has no effect...
Autores principales: | Piccinni, Marie-Pierre, Lombardelli, Letizia, Logiodice, Federica, Kullolli, Ornela, Maggi, Enrico, Barkley, Marylynn S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6456711/ https://www.ncbi.nlm.nih.gov/pubmed/31001262 http://dx.doi.org/10.3389/fimmu.2019.00642 |
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