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Chronic Microglial Activation in the GFAP-IL6 Mouse Contributes to Age-Dependent Cerebellar Volume Loss and Impairment in Motor Function

Chronic microglial activation is a prominent feature of many chronic neurodegenerative diseases, including Parkinson’s and Alzheimer’s disease. To investigate the effects of chronic microglial activation on cerebellar structure and motor function throughout the lifespan, the transgenic GFAP-IL6 mous...

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Detalles Bibliográficos
Autores principales:	Gyengesi, Erika, Rangel, Alejandra, Ullah, Faheem, Liang, Huazheng, Niedermayer, Garry, Asgarov, Rustam, Venigalla, Madhuri, Gunawardena, Dhanushka, Karl, Tim, Münch, Gerald
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6456818/ https://www.ncbi.nlm.nih.gov/pubmed/31001075 http://dx.doi.org/10.3389/fnins.2019.00303

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