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Improving the sensitivity of long read overlap detection using grouped short k-mer matches

BACKGROUND: Single-molecule, real-time sequencing (SMRT) developed by Pacific BioSciences produces longer reads than second-generation sequencing technologies such as Illumina. The increased read length enables PacBio sequencing to close gaps in genome assembly, reveal structural variations, and cha...

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Detalles Bibliográficos
Autores principales: Du, Nan, Chen, Jiao, Sun, Yanni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6456931/
https://www.ncbi.nlm.nih.gov/pubmed/30967123
http://dx.doi.org/10.1186/s12864-019-5475-x