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Improving the sensitivity of long read overlap detection using grouped short k-mer matches
BACKGROUND: Single-molecule, real-time sequencing (SMRT) developed by Pacific BioSciences produces longer reads than second-generation sequencing technologies such as Illumina. The increased read length enables PacBio sequencing to close gaps in genome assembly, reveal structural variations, and cha...
Autores principales: | Du, Nan, Chen, Jiao, Sun, Yanni |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6456931/ https://www.ncbi.nlm.nih.gov/pubmed/30967123 http://dx.doi.org/10.1186/s12864-019-5475-x |
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