Cargando…

Transiently proliferating perivascular microglia harbor M1 type and precede cerebrovascular changes in a chronic hypertension model

BACKGROUND: Microglia play crucial roles in the maintenance of brain homeostasis. Activated microglia show a biphasic influence, promoting beneficial repair and causing harmful damage via M2 and M1 microglia, respectively. It is well-known that microglia are initially activated to the M2 state and s...

Descripción completa

Detalles Bibliográficos
Autores principales:	Koizumi, Takashi, Taguchi, Katsutoshi, Mizuta, Ikuko, Toba, Hiroe, Ohigashi, Makoto, Onishi, Okihiro, Ikoma, Kazuya, Miyata, Seiji, Nakata, Tetsuo, Tanaka, Masaki, Foulquier, Sébastien, Steinbusch, Harry W. M., Mizuno, Toshiki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6456949/ https://www.ncbi.nlm.nih.gov/pubmed/30971251 http://dx.doi.org/10.1186/s12974-019-1467-7

Ejemplares similares

Vessel-Associated Immune Cells in Cerebrovascular Diseases: From Perivascular Macrophages to Vessel-Associated Microglia
por: Koizumi, Takashi, et al.
Publicado: (2019)

Preconditioning with Short-Term Dietary Restriction Attenuates Cardiac Oxidative Stress and Hypertrophy Induced by Chronic Pressure Overload
por: Kobara, Miyuki, et al.
Publicado: (2021)

Induction of autophagy has protective roles in imatinib-induced cardiotoxicity
por: Kobara, Miyuki, et al.
Publicado: (2021)

Preconditioning by Preceding Ischemic Cerebrovascular Events
por: Correia, Pamela N., et al.
Publicado: (2021)

Mutations in the β-amyloid precursor protein in familial Alzheimer’s disease increase Aβ oligomer production in cellular models
por: Ohshima, Yoichi, et al.
Publicado: (2018)

Histological assessment of cortical bone changes in diabetic rats
por: Minami, Masataka, et al.
Publicado: (2022)

Clinical and Genetic Aspects of CADASIL
por: Mizuno, Toshiki, et al.
Publicado: (2020)

The Adult Human Brain Harbors Multipotent Perivascular Mesenchymal Stem Cells
por: Paul, Gesine, et al.
Publicado: (2012)

Cardiovascular and cerebrovascular–associated mortality in patients with preceding bronchiectasis exacerbation
por: Lee, Sang Chul, et al.
Publicado: (2022)

Association Between Carotid Artery Perivascular Fat Density and Cerebrovascular Ischemic Events
por: Baradaran, Hediyeh, et al.
Publicado: (2018)

Perivascular spaces and brain waste clearance systems: relevance for neurodegenerative and cerebrovascular pathology
por: Gouveia-Freitas, Kaylene, et al.
Publicado: (2021)

Perivascular Adipose Tissue Harbors Atheroprotective IgM-Producing B Cells
por: Srikakulapu, Prasad, et al.
Publicado: (2017)

Early detection of osteoarthritis in rabbits using MRI with a double-contrast agent
por: Onishi, Okihiro, et al.
Publicado: (2018)

Brain Enlarged Perivascular Spaces as Imaging Biomarkers of Cerebrovascular Disease: A Clinical Narrative Review
por: Ramaswamy, Srinath, et al.
Publicado: (2022)

Evaluation of NOTCH3 Pro167Ser Variation in a Japanese Family with Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy
por: Mizuno, Toshiki, et al.
Publicado: (2016)

Kidney Pathology Precedes and Predicts the Pathological Cascade of Cerebrovascular Lesions in Stroke Prone Rats
por: Schreiber, Stefanie, et al.
Publicado: (2011)

Phenotypic Changes in T Cell and Macrophage Subtypes in Perivascular Adipose Tissues Precede High-Fat Diet-Induced Hypertension
por: Kumar, Ramya Kalyana, et al.
Publicado: (2021)

Enhanced Production of (R)-3-Hydroxybutyrate Oligomers by Coexpression of Molecular Chaperones in Recombinant Escherichia coli Harboring a Polyhydroxyalkanoate Synthase Derived from Bacillus cereus YB-4
por: Goto, Saki, et al.
Publicado: (2022)

Sweep imaging with Fourier transform as a tool with MRI for evaluating the effect of teriparatide on cortical bone formation in an ovariectomized rat model
por: Sotozono, Yasutaka, et al.
Publicado: (2022)

Differential Expression of Alpha-Synuclein in Hippocampal Neurons
por: Taguchi, Katsutoshi, et al.
Publicado: (2014)

Gd-based Contrast Enhancement of the Perivascular Spaces in the Basal Ganglia
por: Naganawa, Shinji, et al.
Publicado: (2016)

Analysis of gut microbiota in patients with cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL)
por: Matsuura, Jun, et al.
Publicado: (2019)

Cerebral Toxoplasmosis Diagnosed by Nested-polymerase Chain Reaction in a Patient with Rheumatoid Arthritis
por: Matsuura, Jun, et al.
Publicado: (2018)

A novel three-base duplication, E243dup, of GFAP identified in a patient with Alexander disease
por: Yasuda, Rei, et al.
Publicado: (2017)

The Role of Perivascular Adipose Tissue in Non-atherosclerotic Vascular Disease
por: Horimatsu, Tetsuo, et al.
Publicado: (2017)

Investigation of the Longitudinal Relaxation Time of Rat Tibial Cortical Bone Using SWIFT
por: Sukenari, Tsuyoshi, et al.
Publicado: (2016)

Heterogeneity of perivascular astrocyte endfeet depending on vascular regions in the mouse brain
por: Kameyama, Takeshi, et al.
Publicado: (2023)

Enlarged perivascular spaces are associated with the disease activity in systemic lupus erythematosus
por: Miyata, Mari, et al.
Publicado: (2017)

Pharmacological depletion of microglia and perivascular macrophages prevents Vascular Cognitive Impairment in Ang II-induced hypertension
por: Kerkhofs, Danielle, et al.
Publicado: (2020)

Reactive Oxygen Species in the Aorta and Perivascular Adipose Tissue Precedes Endothelial Dysfunction in the Aorta of Mice with a High-Fat High-Sucrose Diet and Additional Factors
por: Osaki, Ayumu, et al.
Publicado: (2023)

CADASIL Presenting as Acute Bilateral Multiple Subcortical Infarcts without a Characteristic Temporal Pole or Any External Capsule Lesions
por: Ando, Takashi, et al.
Publicado: (2016)

A Japanese Case of CADASIL with a Rare Mutation in Exon 24 of the NOTCH3 Gene
por: Ebihara, Yuka, et al.
Publicado: (2018)

Time course of neuropathological events in hyperhomocysteinemic amyloid depositing mice reveals early neuroinflammatory changes that precede amyloid changes and cerebrovascular events
por: Weekman, Erica M., et al.
Publicado: (2019)

Dec1 Deficiency Suppresses Cardiac Perivascular Fibrosis Induced by Transverse Aortic Constriction
por: Le, Hue Thi, et al.
Publicado: (2019)

Precedence
Publicado: (1875)

Prevalence and Atypical Clinical Characteristics of NOTCH3 Mutations Among Patients Admitted for Acute Lacunar Infarctions
por: Okada, Takashi, et al.
Publicado: (2020)

Optimization of Culture Conditions for Secretory Production of 3-Hydroxybutyrate Oligomers Using Recombinant Escherichia coli
por: Sakurai, Tetsuo, et al.
Publicado: (2022)

Preceding psychological factors and calorie intake in patients with type 2 diabetes: investigation by ecological momentary assessment
por: Inada, Shuji, et al.
Publicado: (2019)

Association between cerebrovasoreactivity and stroke in cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy
por: Mukai, Mao, et al.
Publicado: (2023)

Differences in Signal Intensity and Enhancement on MR Images of the Perivascular Spaces in the Basal Ganglia versus Those in White Matter
por: Naganawa, Shinji, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_6s96th83qbm63qnnq8gvpsnegu