Clusterin silencing restores myoblasts viability and down modulates the inflammatory process in osteoporotic disease

BACKGROUND: Targeting new molecular pathways leading to Osteoporosis (OP) and Osteoarthritis (OA) is a hot topic for drug discovery. Clusterin (CLU) is a glycoprotein involved in inflammation, proliferation, cell death, neoplastic disease, Alzheimer disease and aging. The present study focuses on th...

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Detalles Bibliográficos
Autores principales: Pucci, S., Greggi, C., Polidoro, C., Piro, M. C., Celi, M., Feola, M., Gasbarra, E., Iundusi, R., Mastrangeli, F., Novelli, G., Orlandi, A., Tarantino, U.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6457035/
https://www.ncbi.nlm.nih.gov/pubmed/30967152
http://dx.doi.org/10.1186/s12967-019-1868-5

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