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A Mild, DNA-Compatible Nitro Reduction Using B(2)(OH)(4)

[Image: see text] A hypodiboric acid system for the reduction of nitro groups on DNA–chemical conjugates has been developed. This transformation provided good to excellent yields of the reduced amine product for a variety of functionalized aromatic, heterocyclic, and aliphatic nitro compounds. DNA t...

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Detalles Bibliográficos
Autores principales:	Du, Huang-Chi, Simmons, Nicholas, Faver, John C., Yu, Zhifeng, Palaniappan, Murugesan, Riehle, Kevin, Matzuk, Martin M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2019
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6457042/ https://www.ncbi.nlm.nih.gov/pubmed/30860855 http://dx.doi.org/10.1021/acs.orglett.9b00497

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