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Deficiency of Yes-Associated Protein Induces Cataract in Mice

Cataract is a major cause of blindness worldwide, its complicated and unclear etiopathogenesis limit effective therapy. Here, we found that Yap, a downstream effector of the Hippo pathway, is specifically expressed in lens epithelial cells and Yap conditional knockout (cKO) in the lens leads to cata...

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Detalles Bibliográficos
Autores principales: He, Qing, Gao, Yuhao, Wang, Tongxing, Zhou, Lujun, Zhou, Wenxia, Yuan, Zengqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: JKL International LLC 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6457047/
https://www.ncbi.nlm.nih.gov/pubmed/31011480
http://dx.doi.org/10.14336/AD.2018.0910