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Processing of Mutant β-Amyloid Precursor Protein and the Clinicopathological Features of Familial Alzheimer’s Disease

Alzheimer’s disease (AD) is a complex, multifactorial disease involving many pathological mechanisms. Nonetheless, single pathogenic mutations in amyloid precursor protein (APP) or presenilin 1 or 2 can cause AD with almost all of the clinical and neuropathological features, and therefore, we believ...

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Detalles Bibliográficos
Autores principales:	Bi, Christopher, Bi, Stephanie, Li, Bin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	JKL International LLC 2019
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6457050/ https://www.ncbi.nlm.nih.gov/pubmed/31011484 http://dx.doi.org/10.14336/AD.2018.0425

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