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Smooth muscle cell-specific knockout of neuropilin-1 impairs postnatal lung development and pathological vascular smooth muscle cell accumulation

Neuropilin 1 (NRP1) is important for neuronal and cardiovascular development due to its role in conveying class 3 semaphorin and vascular endothelial growth factor signaling, respectively. NRP1 is expressed in smooth muscle cells (SMCs) and mediates their migration and proliferation in cell culture...

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Detalles Bibliográficos
Autores principales: Mahmoud, Marwa, Evans, Ian M., Mehta, Vedanta, Pellet-Many, Caroline, Paliashvili, Ketevan, Zachary, Ian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Physiological Society 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6457104/
https://www.ncbi.nlm.nih.gov/pubmed/30649916
http://dx.doi.org/10.1152/ajpcell.00405.2018