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Smooth muscle cell-specific knockout of neuropilin-1 impairs postnatal lung development and pathological vascular smooth muscle cell accumulation
Neuropilin 1 (NRP1) is important for neuronal and cardiovascular development due to its role in conveying class 3 semaphorin and vascular endothelial growth factor signaling, respectively. NRP1 is expressed in smooth muscle cells (SMCs) and mediates their migration and proliferation in cell culture...
Autores principales: | Mahmoud, Marwa, Evans, Ian M., Mehta, Vedanta, Pellet-Many, Caroline, Paliashvili, Ketevan, Zachary, Ian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Physiological Society
2019
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6457104/ https://www.ncbi.nlm.nih.gov/pubmed/30649916 http://dx.doi.org/10.1152/ajpcell.00405.2018 |
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