Galantamine-memantine combination superior to donepezil-memantine combination in Alzheimer’s disease: critical dissection with an emphasis on kynurenic acid and mismatch negativity

BACKGROUND: The donepezil-memantine combination is a US Food and Drug Administration (FDA)–approved medication to treat Alzheimer’s disease (AD). Galantamine is superior to donepezil because it is a positive allosteric modulator of the alpha-7 nicotinic acetylcholine receptor (α7nAChR). Although gal...

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Detalles Bibliográficos
Autores principales: Koola, Maju Mathew, Nikiforuk, Agnieszka, Pillai, Anilkumar, Parsaik, Ajay K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
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Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6457262/
https://www.ncbi.nlm.nih.gov/pubmed/30984874

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