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Glutathione Peroxidase 1 Promotes NSCLC Resistance to Cisplatin via ROS-Induced Activation of PI3K/AKT Pathway

PURPOSE: Reactive oxygen species (ROS)-induced cytotoxicity is an important mechanism by which cisplatin kills tumor cells. Glutathione peroxidase family (GPXs) is an important member of antioxidant system which metabolizes intracellular ROS and maintains homeostasis of cells. Altered expressions of...

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Detalles Bibliográficos
Autores principales:	Chen, Baishen, Shen, Zhuojian, Wu, Duoguang, Xie, Xuan, Xu, Xia, Lv, Liangzhan, Dai, Honglue, Chen, Ju, Gan, Xiangfeng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6457285/ https://www.ncbi.nlm.nih.gov/pubmed/31032363 http://dx.doi.org/10.1155/2019/7640547

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