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Monodisperse polysarcosine-based highly-loaded antibody-drug conjugates

Antibody-drug conjugates (ADCs) convey highly potent anticancer drugs to antigen-expressing tumor cells, thereby sparing healthy tissues throughout the body. Pharmacokinetics and tolerability of ADCs are predominantly influenced by the drug-antibody ratio (DAR) of the conjugates, which is to-date li...

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Detalles Bibliográficos
Autores principales:	Viricel, Warren, Fournet, Guy, Beaumel, Sabine, Perrial, Emeline, Papot, Sébastien, Dumontet, Charles, Joseph, Benoît
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Royal Society of Chemistry 2019
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6457330/ https://www.ncbi.nlm.nih.gov/pubmed/31015945 http://dx.doi.org/10.1039/c9sc00285e

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