Experimentally reduced insulin/IGF‐1 signaling in adulthood extends lifespan of parents and improves Darwinian fitness of their offspring

Classical theory maintains that ageing evolves via energy trade‐offs between reproduction and survival leading to accumulation of unrepaired cellular damage with age. In contrast, the emerging new theory postulates that ageing evolves because of deleterious late‐life hyper‐function of reproduction‐p...

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Detalles Bibliográficos
Autores principales: Lind, Martin I., Ravindran, Sanjana, Sekajova, Zuzana, Carlsson, Hanne, Hinas, Andrea, Maklakov, Alexei A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Letters
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6457396/
https://www.ncbi.nlm.nih.gov/pubmed/31007945
http://dx.doi.org/10.1002/evl3.108

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