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A novel score in the prediction of rhythm outcome after ablation of atrial fibrillation: The SUCCESS score
OBJECTIVE: The aim of the present study was to assess the predictive value of the CHADS(2), CHA(2)DS(2)-VASc, R(2)CHADS(2), and APPLE scores for rhythm outcome in patients with atrial fibrillation (AF) after catheter ablation. METHODS: The cohort of the present study consisted of 192 patients with A...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Kare Publishing
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6457407/ https://www.ncbi.nlm.nih.gov/pubmed/30821714 http://dx.doi.org/10.14744/AnatolJCardiol.2018.76570 |
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author | Jud, Fabian Nicolas Obeid, Slayman Duru, Fırat Haegeli, Laurent Max |
author_facet | Jud, Fabian Nicolas Obeid, Slayman Duru, Fırat Haegeli, Laurent Max |
author_sort | Jud, Fabian Nicolas |
collection | PubMed |
description | OBJECTIVE: The aim of the present study was to assess the predictive value of the CHADS(2), CHA(2)DS(2)-VASc, R(2)CHADS(2), and APPLE scores for rhythm outcome in patients with atrial fibrillation (AF) after catheter ablation. METHODS: The cohort of the present study consisted of 192 patients with AF who underwent a total of 265 ablations. Rhythm outcome was documented between 3 and 24 month after ablation. The mentioned scores were calculated for every patient. RESULTS: Of the patients, 139 (72%) were successfully treated having freedom of any atrial tachyarrhythmia, whereas 21 (11%) had partial success, and 32 (17%) had failure. For univariate analysis, the APPLE score was the only significant predictor of outcome after ablation with an odds ratio (OR) of 1.485 [95% confidence interval (CI) 1.075–2.052, p-value 0.017]. A multivariate binary regression corrected for possible confounders showed that the APPLE score (OR 1.527, 95% CI 1.082–2.153, p-value 0.016) along with the number of previous ablations (OR 5.831, 95% CI 1.356–25.066, p-value 0.018) is a significant predictor of outcome. A novel score (SUCCESS) was created by adding one point to the APPLE score for each previously performed ablation. This novel score demonstrated an improvement in receiver operating characteristic curve analysis (area under the curve 0.657 vs. 0.620). However, these findings were not significant in our study (p-value 0.219). CONCLUSION: Both the APPLE and the novel SUCCESS scores are superior to the CHADS(2), CHA(2)DS(2)-VASc, and R(2)CHADS(2) scores in predicting AF recurrence after catheter ablation. The SUCCESS score appears to have a higher predictive value than the APPLE score and might be a valuable tool to estimate the risk of AF recurrence in patients eligible for catheter ablation. |
format | Online Article Text |
id | pubmed-6457407 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Kare Publishing |
record_format | MEDLINE/PubMed |
spelling | pubmed-64574072019-04-18 A novel score in the prediction of rhythm outcome after ablation of atrial fibrillation: The SUCCESS score Jud, Fabian Nicolas Obeid, Slayman Duru, Fırat Haegeli, Laurent Max Anatol J Cardiol Original Investigation OBJECTIVE: The aim of the present study was to assess the predictive value of the CHADS(2), CHA(2)DS(2)-VASc, R(2)CHADS(2), and APPLE scores for rhythm outcome in patients with atrial fibrillation (AF) after catheter ablation. METHODS: The cohort of the present study consisted of 192 patients with AF who underwent a total of 265 ablations. Rhythm outcome was documented between 3 and 24 month after ablation. The mentioned scores were calculated for every patient. RESULTS: Of the patients, 139 (72%) were successfully treated having freedom of any atrial tachyarrhythmia, whereas 21 (11%) had partial success, and 32 (17%) had failure. For univariate analysis, the APPLE score was the only significant predictor of outcome after ablation with an odds ratio (OR) of 1.485 [95% confidence interval (CI) 1.075–2.052, p-value 0.017]. A multivariate binary regression corrected for possible confounders showed that the APPLE score (OR 1.527, 95% CI 1.082–2.153, p-value 0.016) along with the number of previous ablations (OR 5.831, 95% CI 1.356–25.066, p-value 0.018) is a significant predictor of outcome. A novel score (SUCCESS) was created by adding one point to the APPLE score for each previously performed ablation. This novel score demonstrated an improvement in receiver operating characteristic curve analysis (area under the curve 0.657 vs. 0.620). However, these findings were not significant in our study (p-value 0.219). CONCLUSION: Both the APPLE and the novel SUCCESS scores are superior to the CHADS(2), CHA(2)DS(2)-VASc, and R(2)CHADS(2) scores in predicting AF recurrence after catheter ablation. The SUCCESS score appears to have a higher predictive value than the APPLE score and might be a valuable tool to estimate the risk of AF recurrence in patients eligible for catheter ablation. Kare Publishing 2019-03 2019-01-30 /pmc/articles/PMC6457407/ /pubmed/30821714 http://dx.doi.org/10.14744/AnatolJCardiol.2018.76570 Text en Copyright: © 2019 Turkish Society of Cardiology http://creativecommons.org/licenses/by-nc-sa/4.0 This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License |
spellingShingle | Original Investigation Jud, Fabian Nicolas Obeid, Slayman Duru, Fırat Haegeli, Laurent Max A novel score in the prediction of rhythm outcome after ablation of atrial fibrillation: The SUCCESS score |
title | A novel score in the prediction of rhythm outcome after ablation of atrial fibrillation: The SUCCESS score |
title_full | A novel score in the prediction of rhythm outcome after ablation of atrial fibrillation: The SUCCESS score |
title_fullStr | A novel score in the prediction of rhythm outcome after ablation of atrial fibrillation: The SUCCESS score |
title_full_unstemmed | A novel score in the prediction of rhythm outcome after ablation of atrial fibrillation: The SUCCESS score |
title_short | A novel score in the prediction of rhythm outcome after ablation of atrial fibrillation: The SUCCESS score |
title_sort | novel score in the prediction of rhythm outcome after ablation of atrial fibrillation: the success score |
topic | Original Investigation |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6457407/ https://www.ncbi.nlm.nih.gov/pubmed/30821714 http://dx.doi.org/10.14744/AnatolJCardiol.2018.76570 |
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