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Estimation of the breadth of CD4bs targeting HIV antibodies by molecular modeling and machine learning
HIV is a highly mutable virus for which all attempts to develop a vaccine have been unsuccessful. Nevertheless, few long-infected patients develop antibodies, called broadly neutralizing antibodies (bnAbs), that have a high breadth and can neutralize multiple variants of the virus. This suggests tha...
Autores principales: | Conti, Simone, Karplus, Martin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6457539/ https://www.ncbi.nlm.nih.gov/pubmed/30970017 http://dx.doi.org/10.1371/journal.pcbi.1006954 |
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