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Mechanistic insights into the SNARE complex disassembly

NSF (N-ethylmaleimide–sensitive factor) and α-SNAP (α–soluble NSF attachment protein) bind to the SNARE (soluble NSF attachment protein receptor) complex, the minimum machinery to mediate membrane fusion, to form a 20S complex, which disassembles the SNARE complex for reuse. We report the cryo-EM st...

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Detalles Bibliográficos
Autores principales: Huang, Xuan, Sun, Shan, Wang, Xiaojing, Fan, Fenghui, Zhou, Qiang, Lu, Shan, Cao, Yong, Wang, Qiu-Wen, Dong, Meng-Qiu, Yao, Jun, Sui, Sen-Fang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6457932/
https://www.ncbi.nlm.nih.gov/pubmed/30989110
http://dx.doi.org/10.1126/sciadv.aau8164

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