Transient activation of the UPR(ER) is an essential step in the acquisition of pluripotency during reprogramming

Somatic cells can be reprogrammed into pluripotent stem cells using the Yamanaka transcription factors. Reprogramming requires both epigenetic landscape reshaping and global remodeling of cell identity, structure, basic metabolic processes, and organelle form and function. We hypothesize that variab...

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Detalles Bibliográficos
Autores principales: Simic, Milos S., Moehle, Erica A., Schinzel, Robert T., Lorbeer, Franziska K., Halloran, Jonathan J., Heydari, Kartoosh, Sanchez, Melissa, Jullié, Damien, Hockemeyer, Dirk, Dillin, Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6457941/
https://www.ncbi.nlm.nih.gov/pubmed/30989118
http://dx.doi.org/10.1126/sciadv.aaw0025

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6457941/
https://www.ncbi.nlm.nih.gov/pubmed/30989118
http://dx.doi.org/10.1126/sciadv.aaw0025

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