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A ubiquitin-dependent signaling axis specific for ALKBH-mediated DNA dealkylation repair

DNA repair is essential to prevent the cytotoxic or mutagenic effects of various types of DNA lesions, which are sensed by distinct pathways to recruit repair factors specific to the damage type. Although biochemical mechanisms for repairing several forms of genomic insults are well understood, the...

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Detalles Bibliográficos
Autores principales:	Brickner, Joshua R., Soll, Jennifer M., Lombardi, Patrick M., Vågbø, Cathrine B., Mudge, Miranda C., Oyeniran, Clement, Rabe, Renana, Jackson, Jessica, Sullender, Meagan E., Blazosky, Elyse, Byrum, Andrea K., Zhao, Yu, Corbett, Mark A., Gécz, Jozef, Field, Michael, Vindigni, Alessandro, Slupphaug, Geir, Wolberger, Cynthia, Mosammaparast, Nima
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6458054/ https://www.ncbi.nlm.nih.gov/pubmed/29144457 http://dx.doi.org/10.1038/nature24484

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